How It Works: The Science of Nicotinamide Riboside and NAD+ Restoration

Aging isn’t just about passing years. It’s about the steady loss of cellular energy and repair capacity.
One of the most important molecules behind that process is NAD+ (nicotinamide adenine dinucleotide). It is required by every cell in your body to produce energy, repair DNA, regulate metabolism, and maintain mitochondrial function.

As we age, NAD+ levels decline significantly. By middle age, many people have lost up to half of their natural NAD+ supply. This loss has been directly linked to increased fatigue, reduced cognitive performance, slower repair, and weaker overall resilience.

That’s where Pure NR becomes essential.

1) Nicotinamide Riboside Is a Direct NAD+ Precursor

Pure NR is a bioavailable form of Vitamin B3 that converts efficiently into NAD+ through the salvage pathway. By restoring this critical coenzyme, Pure NR helps reactivate the body’s natural systems for energy production, cellular repair, and defense.

2) Pure NR Is Designed for Research and Trusted in Clinical Trials

While most NR ingredients are manufactured for the supplement market, Pure NR is produced to meet the standards of scientific research.

At DoNotAge.org, we test and verify every batch to ensure maximum purity and stability. That’s why researchers across the globe rely on our NR in active clinical studies related to aging, energy metabolism, brain health, and more.

3) NAD+ Supports Vital Systems Throughout the Body

Increasing NAD+ impacts nearly every part of your biology. Benefits seen in research include:

✔ Cellular Energy – Supports ATP production inside mitochondria to reduce fatigue and enhance vitality*
✔ Cognitive Function – Promotes brain cell metabolism and healthy neurological aging*
✔ DNA Repair – Fuels essential repair enzymes that protect genome integrity*
✔ Metabolic Balance – Helps regulate glucose metabolism and insulin sensitivity*
✔ Muscle Recovery – Enhances mitochondrial renewal in muscle tissue for strength and recovery*
✔ Healthy Inflammation Response – Supports cellular resilience under oxidative stress*
✔ Cardiovascular Support – Assists healthy blood flow and vascular function*

At DoNotAge.org, we don’t follow supplement trends. We fund and lead the research that shapes the future of health. Pure NR is developed with uncompromising standards to meet the needs of clinical researchers and those who take their health seriously.

BENEFITS OF HYDROLYSED COLLAGEN PEPTIDES

✔ Rebuilds Joint Strength – Supports healthy cartilage and connective tissue to improve flexibility and mobility.*

✔ Improves Skin Elasticity – Promotes smoother, firmer, and more hydrated skin by restoring internal collagen levels.*

✔ Supports Bone Density – Contributes to stronger bones by delivering amino acids essential for skeletal integrity.*

✔ Enhances Tissue Repair & Recovery – Accelerates recovery from physical activity or injury by nourishing muscle and tendon structure.*

✔ Strengthens Hair & Nails – Provides structural proteins that support keratin production for healthier hair and nail growth.*

✔ Promotes Gut & Tissue Barrier Health – Helps maintain the integrity of the gut lining and other connective tissue systems.*

✔ Sustains Structural Longevity – Reinforces the body’s internal framework to resist age-related breakdown over time.*

PRODUCT DETAILS

✔ Type I & III Collagen Peptides – Sourced from 100% grass-fed bovine to match the body’s most abundant collagen types.*

✔ Low-Temperature Enzymatic Hydrolysis – Preserves peptide structure for enhanced bioavailability and absorption.*

✔ Research-Leading Amino Acid Profile – Rich in glycine, proline, and hydroxyproline key to collagen production and tissue regeneration.*

✔ Unflavored & Easily Mixable – Neutral taste blends seamlessly into hot or cold liquids without altering flavor or texture.*

✔ Zero Fillers or Additives – Free from sweeteners, binders, preservatives, or artificial ingredients.*

✔ Non-GMO & Hormone-Free – Sourced from pasture-raised cattle with no added hormones or antibiotics.*

✔ Rigorously Tested In-House for Purity & Consistency – Every batch undergoes internal quality control to confirm molecular weight, peptide concentration, and absence of contaminants.*

At DoNotAge.org we prioritise health over hype, delivering ingredients used in global research, not just marketed as supplements.

Pure NR – Cellular Energy, Repair, and Healthy Aging

At DoNotAge.org, we don’t follow trends. We lead the research. Pure NR is formulated with high-purity Nicotinamide Riboside, a clinically relevant precursor to NAD+, one of the most vital coenzymes for human health. As NAD+ levels decline with age, the body’s ability to generate energy, repair DNA, and maintain cellular function declines as well. Pure NR helps restore what aging takes away.

Trusted by global researchers and used in clinical trials, Nicotinamide Riboside is one of the most studied compounds for its impact on mitochondrial function, cellular resilience, and metabolic health.

Scientific studies show that Nicotinamide Riboside helps:

✔ Restore Cellular Energy – Boosts NAD+ levels to support mitochondrial ATP production and reduce fatigue*
✔ Support Brain Function – Enhances neuronal energy metabolism and supports cognitive clarity*
✔ Promote DNA Repair – Fuels enzymes like PARPs and sirtuins responsible for maintaining genome stability*
✔ Balance Metabolic Health – Supports glucose metabolism and insulin sensitivity across multiple systems*
✔ Support Healthy Aging – Reinforces your body’s natural repair and renewal processes as you age*

Not all NR is created equal. If you’re serious about long-term health, you deserve an ingredient that meets research standards. No fillers. No shortcuts. Just clinically trusted Nicotinamide Riboside, verified for purity and built for results.

We are committed to delivering the most scientifically advanced health solutions in the world. Pure NR is a direct reflection of that mission, clean, potent, and designed to restore your body from the inside out.